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  1. Medical and Biological Engineering and Computing
  2. Medical and Biological Engineering and Computing : Volume 45
  3. Medical and Biological Engineering and Computing : Volume 45, Issue 5, May 2007
  4. Stented artery biomechanics and device design optimization
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Medical and Biological Engineering and Computing : Volume 55
Medical and Biological Engineering and Computing : Volume 54
Medical and Biological Engineering and Computing : Volume 53
Medical and Biological Engineering and Computing : Volume 52
Medical and Biological Engineering and Computing : Volume 51
Medical and Biological Engineering and Computing : Volume 50
Medical and Biological Engineering and Computing : Volume 49
Medical and Biological Engineering and Computing : Volume 48
Medical and Biological Engineering and Computing : Volume 47
Medical and Biological Engineering and Computing : Volume 46
Medical and Biological Engineering and Computing : Volume 45
Medical and Biological Engineering and Computing : Volume 45, Issue 12, December 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 11, November 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 10, October 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 9, September 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 8, August 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 7, July 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 6, June 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 5, May 2007
Laser Doppler perfusion monitoring and imaging: novel approaches
Robust propagation velocity estimation of gastric electrical activity by least mean p-norm blind channel identification
Electro-mechanical stability of surface EMG sensors
Numerical model for RF capacitive regional deep hyperthermia in pelvic tumors
Virtual prototyping of a brace design for the correction of scoliotic deformities
Recognizing knee pathologies by classifying instantaneous screws of the six degrees-of-freedom knee motion
Nearly automated analysis of coronary Doppler flow velocity from transthoracic ultrasound images: validation with manual tracings
Removal of ocular artifacts from the EEG: a comparison between time-domain regression method and adaptive filtering method using simulated data
Stented artery biomechanics and device design optimization
Medical and Biological Engineering and Computing : Volume 45, Issue 4, April 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 3, March 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 2, February 2007
Medical and Biological Engineering and Computing : Volume 45, Issue 1, January 2007
Medical and Biological Engineering and Computing : Volume 44
Medical and Biological Engineering and Computing : Volume 43
Medical and Biological Engineering and Computing : Volume 42
Medical and Biological Engineering and Computing : Volume 41
Medical and Biological Engineering and Computing : Volume 40
Medical and Biological Engineering and Computing : Volume 39
Medical and Biological Engineering and Computing : Volume 38
Medical and Biological Engineering and Computing : Volume 37
Medical and Biological Engineering and Computing : Volume 36
Medical and Biological Engineering and Computing : Volume 35

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Stented artery biomechanics and device design optimization

Content Provider SpringerLink
Author Timmins, Lucas H. More, Michael R. Meyer, Clark A. Criscione, John C. Rachev, Alexander Moore, James E.
Copyright Year 2007
Abstract The deployment of a vascular stent aims to increase lumen diameter for the restoration of blood flow, but the accompanied alterations in the mechanical environment possibly affect the long-term patency of these devices. The primary aim of this investigation was to develop an algorithm to optimize stent design, allowing for consideration of competing solid mechanical concerns (wall stress, lumen gain, and cyclic deflection). Finite element modeling (FEM) was used to estimate artery wall stress and systolic/diastolic geometries, from which single parameter outputs were derived expressing stress, lumen gain, and cyclic artery wall deflection. An optimization scheme was developed using Lagrangian interpolation elements that sought to minimize the sum of these outputs, with weighting coefficients. Varying the weighting coefficients results in stent designs that prioritize one output over another. The accuracy of the algorithm was confirmed by evaluating the resulting outputs of the optimized geometries using FEM. The capacity of the optimization algorithm to identify optimal geometries and their resulting mechanical measures was retained over a wide range of weighting coefficients. The variety of stent designs identified provides general guidelines that have potential clinical use (i.e., lesion-specific stenting).
Starting Page 505
Ending Page 513
Page Count 9
File Format PDF
ISSN 01400118
Journal Medical and Biological Engineering and Computing
Volume Number 45
Issue Number 5
e-ISSN 17410444
Language English
Publisher Springer-Verlag
Publisher Date 2007-03-21
Publisher Place Berlin, Heidelberg
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Stress Restenosis Intervention Lumen Inflammation Neurosciences Computer Applications Imaging Radiology Human Physiology Biomedical Engineering
Content Type Text
Resource Type Article
Subject Biomedical Engineering Computer Science Applications
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