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  1. Archives of Environmental Contamination and Toxicology
  2. Archives of Environmental Contamination and Toxicology : Volume 64
  3. Archives of Environmental Contamination and Toxicology : Volume 64, Issue 3, April 2013
  4. Nandrolone Decanoate Induces Genetic Damage in Multiple Organs of Rats
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Archives of Environmental Contamination and Toxicology : Volume 72
Archives of Environmental Contamination and Toxicology : Volume 71
Archives of Environmental Contamination and Toxicology : Volume 70
Archives of Environmental Contamination and Toxicology : Volume 69
Archives of Environmental Contamination and Toxicology : Volume 68
Archives of Environmental Contamination and Toxicology : Volume 67
Archives of Environmental Contamination and Toxicology : Volume 66
Archives of Environmental Contamination and Toxicology : Volume 65
Archives of Environmental Contamination and Toxicology : Volume 64
Archives of Environmental Contamination and Toxicology : Volume 64, Issue 4, May 2013
Archives of Environmental Contamination and Toxicology : Volume 64, Issue 3, April 2013
Quantification of Environmental Tobacco Smoke Contribution on Outdoor Particulate Aliphatic and Polycyclic Aromatic Hydrocarbons
Geochemical Characterization of Acid Mine Lakes in Northwest Turkey and Their Effect on the Environment
Ecotoxicity of Cr, Cd, and Pb on Two Mediterranean Soils
Metal Contamination Disturbs Biochemical and Microbial Properties of Calcareous Agricultural Soils of the Mediterranean Area
Impact of Pesticide Contamination on Aquatic Microorganism Populations in the Littoral Zone
Study on Chromium-Binding Capacity of Callitriche cophocarpa in an Aquatic Environment
Assessing the Chronic Toxicity of Atrazine, Permethrin, and Chlorothalonil to the Cladoceran Ceriodaphnia cf. dubia in Laboratory and Natural River Water
Chronic Effects of Carbamazepine on Life-History Strategies of Ceriodaphnia dubia in Three Successive Generations
Application of a Biomarker Response Index for Ranking the Toxicity of Five Pharmaceutical and Personal Care Products (PPCPs) to the Bivalve Dreissena polymorpha
Temporal Trends (2004–2009) of Imposex in Rock Shells Thais clavigera Collected Along the Korean Coast Associated With Tributyltin Regulation in 2003 and 2008
Effects of Sublethal Dose of Fipronil on Neuron Metabolic Activity of Africanized Honeybees
Levels of Mercury in Muscle and Liver of Star-Spotted Dogfish (Mustelus manazo) from the Northern Region of Japan: A Comparison with Spiny Dogfish (Squalus acanthias)
Alterations in Differentially Expressed Genes After Repeated Exposure to Perfluorooctanoate and Perfluorooctanesulfonate in Liver of Oryzias latipes
Assessing Mercury Exposure and Biomarkers in Largemouth Bass (Micropterus Salmoides) from a Contaminated River System in California
Toxicological Effects of the Antibiotic Oxytetracycline to an Indian Major Carp Labeo rohita
Dietary Selenomethionine Exposure Induces Physical Malformations and Decreases Growth and Survival to Metamorphosis in an Amphibian (Hyla chrysoscelis)
Nandrolone Decanoate Induces Genetic Damage in Multiple Organs of Rats
Exposure Assessment of Organochlorine Pesticides, Arsenic, and Lead in Children From the Major Agricultural Areas in Sonora, Mexico
Archives of Environmental Contamination and Toxicology : Volume 64, Issue 2, February 2013
Archives of Environmental Contamination and Toxicology : Volume 64, Issue 1, January 2013
Archives of Environmental Contamination and Toxicology : Volume 63
Archives of Environmental Contamination and Toxicology : Volume 62
Archives of Environmental Contamination and Toxicology : Volume 61
Archives of Environmental Contamination and Toxicology : Volume 60
Archives of Environmental Contamination and Toxicology : Volume 59
Archives of Environmental Contamination and Toxicology : Volume 58
Archives of Environmental Contamination and Toxicology : Volume 57
Archives of Environmental Contamination and Toxicology : Volume 56
Archives of Environmental Contamination and Toxicology : Volume 55
Archives of Environmental Contamination and Toxicology : Volume 54
Archives of Environmental Contamination and Toxicology : Volume 53
Archives of Environmental Contamination and Toxicology : Volume 52
Archives of Environmental Contamination and Toxicology : Volume 51
Archives of Environmental Contamination and Toxicology : Volume 50
Archives of Environmental Contamination and Toxicology : Volume 49
Archives of Environmental Contamination and Toxicology : Volume 48
Archives of Environmental Contamination and Toxicology : Volume 47
Archives of Environmental Contamination and Toxicology : Volume 46
Archives of Environmental Contamination and Toxicology : Volume 45
Archives of Environmental Contamination and Toxicology : Volume 44
Archives of Environmental Contamination and Toxicology : Volume 43
Archives of Environmental Contamination and Toxicology : Volume 42
Archives of Environmental Contamination and Toxicology : Volume 41
Archives of Environmental Contamination and Toxicology : Volume 40
Archives of Environmental Contamination and Toxicology : Volume 39
Archives of Environmental Contamination and Toxicology : Volume 38
Archives of Environmental Contamination and Toxicology : Volume 37
Archives of Environmental Contamination and Toxicology : Volume 36
Archives of Environmental Contamination and Toxicology : Volume 35
Archives of Environmental Contamination and Toxicology : Volume 34
Archives of Environmental Contamination and Toxicology : Volume 33
Archives of Environmental Contamination and Toxicology : Volume 32

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Nandrolone Decanoate Induces Genetic Damage in Multiple Organs of Rats

Content Provider SpringerLink
Author Pozzi, Renan Fernandes, Kelly Rosseti Moura, Carolina Foot Gomes Ferrari, Raquel Agnelli Mesquita Fernandes, Kristianne Porta Santos Ren, Ana Claudia Muniz Ribeiro, Daniel Araki
Copyright Year 2012
Abstract To evaluate the impact potential of nandrolone decanoate on DNA damage in multiple organs of Wistar rats by means of single-cell gel (comet) assay and micronucleus test. A total of 15 animals were distributed into three groups of five animals each as follows: control group = animal not exposed to nandrolone decanoate; experimental group = animals exposed to nandrolone decanoate for 24 h at 5 mg/kg subcutaneously; and experimental group = animals exposed to nandrolone decanoate for 24 h at 15 mg/kg subcutaneously. Significant statistical differences (p < 0.05) were noted in peripheral blood, liver, and heart cells exposed to nandrolone decanoate at the two doses evaluated. A clear dose–response relationship was observed between groups. Kidney cells showed genetic damage at only the highest dose (15 mg/kg) used. However, micronucleus data did not show remarkable differences among groups. In conclusion, the present study indicates that nandrolone decanoate induces genetic damage in rat blood, liver, heart, and kidney cells as shown by single-cell gel (comet) assay results.
Starting Page 514
Ending Page 518
Page Count 5
File Format PDF
ISSN 00904341
Journal Archives of Environmental Contamination and Toxicology
Volume Number 64
Issue Number 3
e-ISSN 14320703
Language English
Publisher Springer-Verlag
Publisher Date 2012-12-07
Publisher Place New York
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Ecotoxicology Pollution Environmental Health Environmental Chemistry Soil Science & Conservation Environmental Monitoring/Analysis
Content Type Text
Resource Type Article
Subject Pollution Health, Toxicology and Mutagenesis Medicine Toxicology
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